/ Evaluation test
Evaluation test #19832/2017
The growth-pattern of signet ring cell carcinomas are:
They originate frequently in the serosa and extend towards the light.
This tumor displays an expansive and infiltrative growth, disturbing and replacing normal tissue.
They form concentric nests with keratin inside.
Laces of neoplastic cells surround poor cellular areas, well demarcated and partially encapsulated.
The typical location of ulcers produced by gastric carcinomas is in:
Lesser curvature of stomach.
Clinically, gastric ulcers are characterized by:
Anemia and fecal occult blood.
Hemorrhage typically in the chronic form with mane.
Rectorragia and melena.
Neoplastic cells in the signet ring cell carcinoma:
This tumor only is observed in the mucosa, not in deeper layers.
Signet ring cells are a histological finding without diagnostic relevance in dogs.
They are flattened, with scarce cytoplasm and are arranged concentrically, forming "keratin pearls".
They have a broad cytoplasm with a large vacuole containing mucopolysaccharides.
The presence of ulcers in the stomach during necropsy:
The histopathological study of endoscopic biopsies is not useful since the diagnosis is mainly by imaging techniques.
Differential diagnosis must be made with numerous diseases, including neoplasms and chronic kidney disease.
The presence of a blood clot in the center of the lesion is characteristic of a chronic process.
Discards neoplastic etiology as tumors do not produce an increase level of gastric acidity.
- Macroscopic study
- Histological study
- Evaluation test
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