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Morphological diagnosis

Morphologic diagnosis is the interpretation of the lesion.

Non-neoplastic lesions

In the case of non-neoplastic lesions, it consists of:

  1. Organ/tissue.
  2. Lesion: inflammation (nephritis, dermatitis, etc.), or other types of processes: necrosis, infarction, edema, atrophy...
  3. Distribution: focal, focally extensive, multifocal, multifocal to coalescent, diffuse.
  4. Course: acute, acute, subacute, chronic.
  5. Severity: mild, moderate and severe.

Other questions that may arise after diagnosis include:

  1. Etiology/cause:
    • Infectious or parasitic, name of agent.
    • Genetic: name of gene affected.
    • Nutritional: type of deficiency or excess, etc.
  2. Disease name: name by which a particular disease is known. E.g.: chronic granulomatous enteritis is known as Paratuberculosis or Johne's disease.

Neoplastic lesions

In the case of neoplastic lesions:

  1. Organ/tissue.
  2. Type of neoplasm:
    • Epithelial: adenoma/papilloma or carcinoma/adenocarcinoma.
    • Mesenchymal or round cell: -oma or -sarcoma. E.g. fibrosarcoma.
    • Muscular: -oma or -sarcoma. E.g. leiomyoma.
  3. Invasion or not, lymphatic or vascular and metastasis to other organs.